左旋肉碱用于减肥的系统评价
China Pharmacy（2012）
四川大学华西医院
Abstract
目的:系统评价左旋肉碱在减肥方面的作用.方法:按照系统评价的要求,全面检索左旋肉碱用于减肥的随机对照试验,对纳入的文献进行严格的质量评价和Meta分析.结果:2组在体重减轻量[WMD=2.35,95％CI(0.35,4.36),P=0.02]、体重指数降低量[WMD=1.75,95％ CI (0.28,3.22),P=0.02]、腰臀比减小量[WMD=0.04,95％CI(0.03,0.05),P＜0.000 01]、体脂减少量方面[WMD=1.36,95％CI(0.31,2.41),P=0.01]的差异均有统计学意义,在皮褶厚度减小量[WMD=0.36,95％CI(-0.64,1.35),P=0.48]及总不良反应发生率方面[RR=2.00,95％CI(0.81,4.91),P=0.13]的差异无统计学意义.结论:左旋肉碱用于减肥安全、有效,需适当配合运动才能更好地发挥作用.
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Pretraining has recently greatly promoted the development of natural language processing (NLP)We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performanceWe propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generationThe model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in ChineseExperimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performanceUpload PDF to Generate Summary
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