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结直肠恶性肿瘤患者焦虑和抑郁的研究进展

泰然健康网
2025-07-21 23:17

抑郁与焦虑是包括身体、情感、社会因素的一种心理障碍，它在恶性肿瘤患者的诊疗过程中广泛出现。结直肠恶性肿瘤作为我国常见的恶性肿瘤之一，现阶段治疗模式为以手术治疗为主，放疗、化疗和靶向治疗等为辅的多学科综合治疗模式，但是手术、放化疗等可加重患者负面情绪的产生，并导致焦虑与抑郁的发生。恶性肿瘤患者焦虑、抑郁，经常表现为绝望、无助、恐慌等，不仅会造成患者依从性降低使治疗复杂化，还会降低患者的免疫功能，加速疾病进展，直接影响患者生活质量及增加死亡率等。积极的心理干预可有效改善焦虑和抑郁导致的上述问题。焦虑与抑郁的研究和心理干预有望提高恶性肿瘤患者的预后。

Depression and anxiety are psychological disorders that include physical, emotional and social factors, which are widely seen in the diagnosis and treatment of patients with malignant tumors. Colorectal malignancy is one of the common malignant tumors in China. At present, the treatment mode is a multidisciplinary comprehensive treatment mode with surgery as the main treatment and radiotherapy, chemotherapy and targeted therapy as the supplement. However, surgery, radiotherapy and chemotherapy can aggravate the negative emotions of patients, and lead to the occurrence of anxiety and depression. Anxiety and depression in patients with malignant tumors often manifest as despair, helplessness, panic, etc., which will not only complicate the treatment due to reduced patient compliance, but also reduce patients' immune function, accelerate disease progression, directly affect patients' quality of life and increase mortality. Positive psychological intervention can effectively improve the above problems caused by anxiety and depression. Research on anxiety and depression and psychological intervention are expected to improve the prognosis of patients with malignant tumors.

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