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减肥手术与静脉血栓栓塞的短期高风险相关

泰然健康网
2024-12-20 02:04

THURSDAY, May 9, 2024 -- In the short term, bariatric surgery is associated with a greater risk for venous thromboembolism (VTE), but in the long-term, it is associated with lower risk, according to a study published online April 30 in Obesity Surgery.Laura B. Harrington, Ph.D., M.P.H., from Kaiser Permanente Washington Health Research Institute in Seattle, and colleagues evaluated the association between bariatric surgery and long-term VTE risk.

2024年5月9日，星期四——根据4月30日《肥胖手术》在线发布的一项研究，减肥手术在短期内与静脉血栓栓塞（VTE）风险较高有关，但从长期来看，与较低风险相关。西雅图凯撒永久华盛顿健康研究所（KaiserPermanenteWashington HealthResearch Institute）的LauraB.Harrington博士及其同事评估了减肥手术与长期VTE风险之间的关系。

The analysis included 30,171 adults with body mass index ≥35 kg/m2 who underwent bariatric surgery (January 2005 to September 2015) and 218,961 matched nonsurgical patients.The researchers found that at 30 days post-index date, bariatric surgery was associated with a greater VTE risk (adjusted hazard ratio [aHR], 5.01) and greater pulmonary embolism (PE) risk (aHR, 3.93) compared with no bariatric surgery.

这项分析包括30171名成年人的体重指数 ≥接受减肥手术（2005年1月至2015年9月）的35公斤/平方米患者和218961名匹配的非手术患者。研究人员发现，在索引日期后30天，减肥手术与更大的VTE风险相关（调整后的危险比[aHR]， 5.01）和更大的肺栓塞（PE）风险（aHR， 3.93）与没有减肥手术相比。

However, at one year post-index date, bariatric surgery was associated with a lower VTE and PE risk (aHR, 0.52 and 0.30, respectively). Similarly, at five years post-index date, lower VTE and PE risks persisted (aHR, 0.59 and 0.45, respectively).'As patients and their clinicians weigh the risks and benefits of bariatric surgery, our finding provides additional evidence to consider not only the procedure's risks in the short-term, but to balance these with potentially strong long-term benefits,' the authors write.Abstract/Full Text (subscription or payment may be required)Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox..

然而，在索引日期后一年，减肥手术与较低的VTE和PE风险相关（aHR，分别为0.52和0.30）。同样，在指数发布五年后，VTE和PE风险仍然较低（aHR，分别为0.59和0.45）作者写道，随着患者及其临床医生权衡减肥手术的风险和益处，我们的发现提供了额外的证据，不仅可以考虑手术在短期内的风险，还可以平衡这些风险与潜在的强大长期益处。摘要/全文（可能需要订阅或付款）无论您感兴趣的主题是什么，都可以订阅我们的新闻稿，以便在收件箱中获得Drugs.com的最佳信息。。