桑叶提取物、茶多酚及其复配物的抗氧化和降血糖活性
WEI Fang-mei, CHEN Chun, LI Chao, FU Xiong. Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds[J]. Science and Technology of Food Industry, 2018, 39(21): 299-305. DOI: 10.13386/j.issn1002-0306.2018.21.053
Citation: WEI Fang-mei, CHEN Chun, LI Chao, FU Xiong. Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds[J]. Science and Technology of Food Industry, 2018, 39(21): 299-305. DOI: 10.13386/j.issn1002-0306.2018.21.053
桑叶提取物、茶多酚及其复配物的抗氧化和降血糖活性
华南理工大学食品科学与工程学院, 广东广州 510640
详细信息
作者简介:韦芳媚(1991-),女,硕士研究生,研究方向:功能碳水化合物,E-mail:18819455753@163.com。
通讯作者:扶雄(1971-),男,博士,教授,研究方向:功能碳水化合物,E-mail:lfxfu@scut.edu.cn。
中图分类号: TS201.4
计量 文章访问数: 0393 HTML全文浏览量: 059 PDF下载量: 016 出版历程 收稿日期: 2018-01-23 网络出版日期: 2020-11-24 刊出日期: 2018-10-31Antioxidant and Hypoglycemic Activities of Mulberry Leaves Extract,Tea Polyphenols and Their Compounds
School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China
摘要
摘要: 为探讨桑叶提取物(MLE)、茶多酚(TP)及其复配物的抗氧化和降血糖活性,本文考察了MLE、TP及其复配物对DPPH和ABTS+自由基的清除能力和糖尿病关键酶(猪胰腺α-淀粉酶、鼠小肠蔗糖酶和麦芽糖酶)的活性抑制能力。结果表明,TP、MLE-TP复配物以及MLE的抗氧化能力依次减弱,其中MLE-TP复配物的抗氧化能力表现为拮抗作用。MLE-TP复配物对糖尿病关键酶的抑制作用均优于单独MLE和TP。复配物MLE:TP=2:1(w/w)对α-淀粉酶的联合指数CI为0.531,复配物MLE:TP=1:1(w/w)对蔗糖酶和麦芽糖酶的CI分别为0.429和0.452。MLE-TP复配物可以提高糖尿病关键酶的抑制效果,起到协同降血糖的作用。MLE和TP的协同降糖功效,为开发安全和高效的天然降血糖功能食品和相关药物提供理论依据。
Abstract: To investigate the antioxidant and hypoglycemic activities of mulberry leaf extract(MLE),tea polyphenols(TP)and their compounds,the DPPH and ABTS+ free radicals scavenging activities and inhibitory effects on key enzymes linked to diabetes(porcine pancreatic α-amylase,rat intestinal sucrase and maltase)were applied. The results showed that the antioxidant capacity of TP was the strongest,followed by MLE-TP compounds and MLE. And the MLE-TP compounds showed antagonistic effect in terms of the antioxidant activity. The MLE-TP compounds showed stronger inhibitory effects on the key enzymes of diabetes than MLE and TP. The Combination Index(CI)of MLE-TP compound with the mass ratio of 2:1 to α-amylase was 0.531,and the CI values of MLE-TP compound with the mass ratio of 1:1 to sucrose and maltase were 0.429 and 0.452,respectively. The MLE-TP compounds could enhance the inhibitory effects on the key enzymes linked to diabetes indicating synergistic hypoglycemic effects,which provided a theoretical basis for developing safe and effective natural functional products and related drugs for alleviating the diabetes.
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计量 文章访问数: HTML全文浏览量: PDF下载量: 出版历程 收稿日期: 2018-01-23 网络出版日期: 2020-11-24 刊出日期: 2018-10-31目录
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